We thank the NIH 4D Nucleome (4DN) program and the National Cancer Institute for awarding us a new U01 grant of $3.2M. This grant will support our study on the 4DN organization and function in human health and disease. This is also our 4th major NIH grant received in the past year. A special thanks to the NIH program officers and reviewers for the recognition of the potentials of our research!
Klarissa is a first-year PhD student in the BQBS track of Yale’s BBS program. She was born and raised in Southern California and recently graduated with a combined bachelor’s and master’s degree in Biochemistry from Brandeis University. In her undergraduate research, she studied the dynamic regulation of Abl kinase to better understand the evolution of regulation in the non-receptor tyrosine kinase family. Specifically, she focused on the interplay between inactivation by myristoylation and activation by phosphorylation. In her graduate work, Klarissa hopes to broaden her horizons and make clinically relevant discoveries. She is excited to work with Dr. Wang to learn microscopy techniques and contribute to a better understanding of the structures and interactions which regulate gene expression. Outside of the lab, Klarissa enjoys baking (both breads and pastries), knitting, and singing with her friends. Welcome, Klarissa!
Our Tiffani (Shengyan) passed her general exam on Thursday Aug 13, 2020. Well done, Master Jin!
We thank National Human Genome Research Institute for awarding us a new R01 award of $2.1M. This grant will support our novel 3D genomic technology developments.
Our Yubao passed his general exam on Wednesday July 29, 2020. Well done, Master Cheng!
We thank National Cancer Institute for awarding us a new R33 award of $1.2M. This grant will support our study of chromatin folding and spatial transcriptomics in cancer.
We thank the organizers of the Fragile Nucleosome seminars for this opportunity to present our work!
Congratulations to all authors!
Liu, M., Lu, Y., Yang, B. et al. Multiplexed imaging of nucleome architectures in single cells of mammalian tissue. Nat Commun 11, 2907 (2020). https://doi.org/10.1038/s41467-020-16732-5
https://www.nature.com/articles/s41467-020-16732-5
We just learnt that former lab member Yanfang Lu successfully defended his PhD dissertation yesterday with a score of five stars (perfect score)! Yanfang performed the majority of his PhD research as a visiting graduate student in our lab. Congratulations to now Dr. Yanfang Lu on this well-deserved title!
