Zhen obtained his PhD degree from Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, and conducted his first postdoctoral research in the same institute. His previous research focused on using mouse spermatogenesis as a model to study dynamic changes and potential functions of different epigenetic modifications. He established high-precision maps of m6A RNA modification and various histone modifications for mouse spermatogenesis, identified key regulatory factors, and elucidated their regulatory mechanisms. Zhen has a strong interest in the regulation of 3D chromatin structure. In our lab here, he hopes to apply imaging-based high-throughput methods to study the dynamic changes in the 3D structure of chromatin during cell development, especially in tumorigenesis. He aims to predict and validate essential regulatory factors at key nodes of tumorigenesis, in order to provide effective targets for clinical diagnosis and treatment of cancer. In his spare time, he enjoys reading, visiting exhibitions, traveling, and spending time with his family.