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  • High-dimensional Statistics
  • Statistical Inference
  • Outlier Detection
  • Machine Learning and Data science
  • Statistical Genetics
  • Immunology
  • Computational Neuroscience


Leying Guan (2020). Conformal prediction with localization.

Leying Guan, Rob Tibshirani (2020). Prediction and outlier detection in classification problems.

Leying Guan (2018). Test Error Estimation after Model Selection Using Validation Error.


Leying Guan, Robert Tibshirani. Post model-fitting exploration via a Next-Door analysis. Canadian Journal of Statistics (2020).

Lisa E Wagar, Christopher R Bolen, Natalia Sigal, Cesar J Lopez Angel, Leying Guan, Beth Kirkpatrick, Rashidul Haque, Robert J Tibshirani, Julie ParsonnetWilliam A Petri and Mark M Davis. Increased T cell differentiation and cytolytic function in Bangladeshi compared to American children. Frontiers in immunology 10 (2019): 2239.

Leying Guan, Xi Chen, Wing Hung Wong. Detecting strong signals in gene perturbation experiments: An adaptive approach with power guarantee and FDR control. Journal of the American Statistical Association (2019): 1-18.

Leying Guan, Xiaoying Tian, Saurabh Gombar, Allison J. Zemek, Gomathi Krishnan, Robert Scott, Balasubramanian Narasimhan, Robert J. Tibshirani, and Tho D. Pham (2017). Big data modeling to predict platelet usage and minimize wastage in a tertiary care system. Proceedings of the National Academy of Sciences, 114(43), pp.11368-11373.

Zhou Fan, and Leying Guan (2017). Approximate l0-penalized estimation of piecewise constant signals on graphs. The Annals of Statistics46(6B), pp.3217-3245.

Ye Henry Li, Dangna Li, Nikolay Samusik, Xiaowei Wang, Leying Guan, Garry P. Nolan, and Wing Hung Wong (2017). Scalable Multi-Sample Single-Cell Data Analysis by Partition-Assisted Clustering and Multiple Alignments of Networks. PLOS Computational Biology13, no. 12

Leying Guan, Zhou Fan, Robert Tibshirani (2016). Regularization for supervised learning via the” hubNet” procedure. Statistica Sinica28, pp.1225-1243.

Leying Guan, Qian Yang, Mengting Gu, Liang Chen, and Xuegong Zhang (2014). Exon expression QTL (eeQTL) analysis highlights distant genomic variations associated with splicing regulation. Quantitative Biology, 2(2), pp.71-79.


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