Our new paper on Piezo2 and mechanosensitivity in duck trigeminal neurons is out in PNAS!
Schneider E*, Anderson E*, Mastrotto M, Matson J, Schulz V, Gallagher P, LaMotte R, Gracheva E, Bagriantsev S. Molecular basis of tactile specialization in the duck bill. PNAS 2017, 114(49): 13036-41. *co-authors
Watch a movie taken by Eve showing mechanoreceptive corpuscle density in the skin of the duck bill. Stunning!
A collaborative study with the Pat Gallagher lab is published!
Glogowska E, Schneider E, Maksimova Y, Schulz V, Lezon-Geyda K, Wu J, Radhakrishnan K, Keel S, Mahoney D, Freidman A, Altura R, Gracheva E, Bagriantsev S, Kalfa T, Gallagher P. Novel mechanisms of PIEZO1 dysfunction in Hereditary Xerocytosis. Blood 2017, 130(16):1845-1856.
A review on Piezo2 in vertebrate mechanoreception in vertebrates is out!
Finding Evan takes on a new meaning…
Anderson EO, Schneider ER, Bagriantsev SN. Piezo2 in cutaneous and proprioceptive mechanotransduction in vertebrates. Curr Top Membr (Piezo channels) 2017, 79: 197-217.
Our recent paper has been highlighted on the PNAS website!
Our paper on TRPV1 from heat-resistant animals is out in PNAS!
Laursen WJ, Schneider ER, Merriman DK, Bagriantsev SN, Gracheva EO. Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels. PNAS 2016, 113(40): 11342-47.
A review on the mechanosensitivity in tactile specialists is out in Physiology:
Schneider ER, Gracheva EO, Bagriantsev SN. Evolutionary specialization of tactile perception in vertebrates. Physiology 2016, 31(3):193-200.
Elena’s collaboration with Polina Lishko is published in Science:
Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith JF, Hill RZ, Bautista DM, Kirichok Y, Lishko PV. Unconventional endocannabinoid signalling governs sperm activation via sex hormone progesterone. Science 2016, Apr29;352(6285):555-9.
Our review on TRPA1 is out in Temperature!
Laursen WJ, Anderson EO, Hoffstaetter L, Bagriantsev SN, Gracheva EO. Species-specific temperature sensitivity of TRPA1. Temperature 2015, 2:1-13.
Authors: Lydia, Willem, Evan, Slav, Elena.
in Current Opinion in Neurobiology.
Gracheva EO, Bagriantsev SN. Evolutionary adaptation to thermosensation. Curr Opin Neurobiol 2015, 34:67-73.
A new publication from our Labs!
Laursen WJ, Mastrotto M, Pesta D, Funk O, Goodman J, Merriman D, Ingolia N, Shulman G, Bagriantsev SN, Gracheva EO. Neuronal UCP1 expression suggests a mechanism for local thermogenesis during torpor. PNAS 2015 (e-pub 01/20).
Warm brains rule!
A review from the labs is out in the Journal of Physiology!
Bagriantsev SN, Gracheva EO. Molecular mechanisms of temperature adaptation. J Physiol 2014 (e-pub 11/28).
This is the fourth review this year from the Slav and Elena groups.
Yes, we have a lot to say.
Two papers from our labs are published in vol. 74 of Current Topics in Membranes!
Laursen WJ, Bagriantsev SN, Gracheva EO. TRPA1 channels: chemical and temperature sensitivity. Curr Top Membr (Thermal sensors) 2014, 74:89-112.
Schneider ER, Anderson EO, Gracheva EO, Bagriantsev SN. Temperature sensitivity of two-pore (K2P) potassium channels. Curr Top Membr (Thermal sensors) 2014, 74: 111-133.
The duck paper is on the cover of PNAS issue 41!
Our review on Piezo proteins is published in JBC!
Bagriantsev SN, Gracheva EO, Gallagher PG. Piezo proteins: regulators of mechanosensation and other cellular processes. J Biol Chem (2014) e-pub Oct 10.
The first research publication from the Slav and Elena Labs at Yale is finally out:
Schneider ER., Mastrotto M, Laursen WJ, Schulz VP, Goodman JB, Funk OH, Gallagher PG, Gracheva EO, Bagriantsev SN. Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl. PNAS (2014) e-pub Sep. 22.
Congratulations to everyone involved!
Special thanks to Margaret Rubega, Kristof Zyskowski, Kenny Dahill, Tina Hotchkiss, Jeffrey Laursen and Charles Pederson for their invaluable input at different stages of this study.
A collaboration with the DeCamilli lab results in the first publication from the Slav and Elena Labs at Yale – in Cell!