Publications

Preprints

Fishbein, S.RS., Wolf, I.D., Dulberger, C.L., Wang, A., Keshishian, H., Wallace, L., Carr, S.A., Ioerger, T.R., Rego, E.H., Rubin, E.J. (2019) A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria bioRxiv,  doi: https://doi.org/10.1101/872341


Gupta, K. R., Rahlwes, K.C., Wang, C., Liu, J., Morita, Y.S., Rego, E.H., (2019) Discovery of an essential mycobacterial polar growth factor involved in cell envelope integrity and LM/LAM transport. doi: https://doi.org/10.1101/633768

Biology

Chen, M., Sun, H., Boot, M., Shao, L., Chang, S., Wang, W., Lam, T.T., Lara-Tejero, M., Rego, E.H., Galan, J.E. (2020) Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella. Science. 369 (6502), 450-455. doi: 10.1126/science.aaz1333


Baranowski C, Welsh MA, Sham LT, Eskandarian HA, Lim HC, Kieser KJ, Wagner JC, McKinney J, Fantner GE, Ioerger TR, Walker S, Bernhardt TG, Rubin EJ, Rego EH. Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape. (2018) eLife  doi:10.7554/eLife.37516. [Epub ahead of print]


Zhu JH, Wang BW, Pan M, Zeng YN, Rego E.H., Javid B. Rifampicin can induce antibiotic tolerance in mycobacterai via paradoxial changes in rpoB transcription (2018) Nature Communications. 9(1):4218. doi: 10.1038/s41467-018-06667-3.


K., Zhang, J., Baranowski, C., Leung, V., Rego, E.H., Morita, Y., Rubin, E.J., Boutte, C.C,  Characterization of conserved and novel septal factors in Mycobacterium smegmatis. (2018) Journal of Bacteriology Feb 23;200(6) doi: 10.1128/JB.00649-17


Rego, E.H., Audette, R.E., and Rubin, E.J. (2017) Deletion of a mycobacterial divisome factor collapses phenotypic heterogeneity, Nature 546 (7656): 153-157. doi:10.1038/nature22361


Kieser, K.J., Boutte, C.C., Kester, J.C., Baer, C.E., Barczak, A.K., Meniche, X, Chao, M.C., Rego, E.H., Sassetti, C.M., Fortune, S.M., Rubin, E.J., (2015). Phosphorylation of the peptidoglycan synthase PonA1 governs the rate of polar growth in mycobacteria. PLOS Pathogens 6(26). doi:10.1371/journal.ppat.1005010


Kannegaard E, Rego E.H, Schuck S, Feldman JL, Marshall W.F. (2014). Quantitative analysis and modeling of katanin function in flagellar length control. Mol Bio Cell. 25(22): 3686-98.

Super-resolution microscopy

Rego, E. H., Shao, L., Macklin, J. J., Winoto, L., Johansson, G. A., Kamps-Hughes, N., Davidson, M. W., and Gustafsson, M.G.L. (2012). Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution.  PNAS 109(3): E135-43.


Fiolka, R., Shao, L., Rego, E.H., Davidson, M.W., and Gustafsson, M.G.L. (2012). Time-lapse two-color 3D imaging of live cells with doubled resolution using structured illumination. PNAS. 109(14): 5311-5315.


Shao, L., Kner, P., Rego, E.H. and Gustafsson, M.G.L. (2011) Super-resolution 3D microscopy of live whole cells using structured illumination. Nature Methods 8(12):1044-6.

Book Chapters and Reviews

Boot, M. and Rego, E.H. Drug Susceptibility of Individual Mycobacterial Cells. Persister Cells and Infectious Disease. edited by Kim Lewis. (2019). 247-272.


Baranowski, C., Rego E.H., Rubin, E.J. (2019). The Dream of a Mycobacterium. Microbiology Spectrum. 7(2).  doi: 10.1128/microbiolspec.GPP3-0008-2018.


Rego, E.H., and Shao, L. Practical Structured-Illumination Microscopy. Methods in Molecular Biology: Advanced Fluorescence Microscopy, Edited by P. Verveer. (2015). 1251:175-92.


Shao, L. and Rego, E.H. Structured Illumination Microscopy. Advanced Fluorescence Microscopy: Super-Resolution and other Novel Techniques, Edited by P.M. Conn and A. Cornea. (2014). 213-24.


Henriques, R., Griffiths, C., Rego, E.H., and Mhlanga, M.M. (2011) PALM and STORM: unlocking live-cell super-resolution. Biopolymers 95 (5): 322-331.