Publications

Articles:

12 Prospects for Riboswitches in Drug Development
Michael G. Mohsen, Ronald R. Breaker*
Methods and Principles in Medicinal Chemistry 2024, in press.
11 Pervasive Transcriptome Interactions of Protein-Targeted Drugs
Linglan Fang, Willem A. Velema, Yujeong Lee, Xiao Lu, Michael G. Mohsen, Anna M. Kietrys, Eric T. Kool*
Nat. Chem. 2023, 15, 1374-1383.  DOI: 10.1038/s41557-023-01309-8
10 In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers
Michael G. Mohsen, Ronald R. Breaker*
Bio-protocol 2023, 13. DOI: 10.21769/BioProtoc.4775
9 Exploiting natural riboswitches for aptamer engineering and validation
Michael G. Mohsen, Matthew K. Midy, Aparaajita Balaji, Ronald R. Breaker*
Nucleic Acids Res. 2023, 51, 966-981. DOI: 10.1093/nar/gkac1218
8 Enhancing Repair of Oxidative DNA Damage with Small Molecule Activators of MTH1
Yujeong Lee, Yoshiyuki Onishi, Lisa A. McPherson, Anna M. Kietrys, Marian Hebenbrock, Yong Woong Jun, Ishani Das, Shanthi Adimoolam, Debin Ji, Michael G. Mohsen, James M. Ford, Eric T. Kool*
ACS Chem. Biol. 2022, 17, 2074-2087. DOI: 10.1021/acschembio.2c00038
7 Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue
Lisa A. McPherson, Clara I. Troccoli, Debin Ji, Annie E. Bowles, Makelle L. Gardiner, Michael G. Mohsen, Nagaraj S. Nagathihalli, Dao M. Nguyen, David J. Robbins, Nipun B. Merchant, Eric T. Kool, Priyamvada Rai*, James M. Ford*
DNA Repair (Amst). 2019, 83, 102644. DOI: 10.1016/j.dnarep.2019.102644
6 Polymerase synthesis of four-base DNA from two stable dimeric nucleotides
Michael G. Mohsen, Debin Ji, Eric T. Kool*
Nucleic Acids Res. 2019, 47, 9495-9501. DOI: 10.1093/nar/gkz741
5 Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus Modifications
Yoel P. Ohayon, Carina Hernandez, Arun Richard Chandrasekaran, Xinyu Wang, Hatem O. Abdallah, Michael Alexander Jong, Michael G. Mohsen, Ruojie Sha, Jens J. Birktoft, Philip S. Lukeman, Paul M. Chaikin, Stephen L. Ginell, Chengde Mao, Nadrian C. Seeman*
ACS Nano 2019, 13, 7957-7965. DOI: 10.1021/acsnano.9b02430
4 Polymerase-amplified release of ATP (POLARA) for detecting single nucleotide variants in RNA and DNA
Michael G. Mohsen, Debin Ji, Eric T. Kool*
Chem. Sci. 2019, 10, 3264-3270. DOI: 10.1039/C8SC03901A
3 The Discovery of Rolling Circle Amplification and Rolling Circle Transcription
Michael G. Mohsen, Eric T. Kool*
Acc. Chem. Res. 2016, 49, 2540-2550. DOI: 10.1021/acs.accounts.6b00417
2 Kinetic selection vs. free energy of DNA base pairing in control of polymerase fidelity
Keriann Oertell, Emily M. Harcourt, Michael G. Mohsen, John Petruska, Eric T. Kool, Myron F. Goodman*
Proc. Natl. Acad. Sci. U. S. A. 2016, 113, E2277-E2285. DOI: 10.1073/pnas.1600279113
1 ATP-Releasing Nucleotides: Linking DNA Synthesis to Luciferase Signaling
Debin Ji, Michael G. Mohsen, Emily M. Harcourt, Eric T. Kool*
Angew. Chem. Intl. Ed. Engl. 2016, 55, 2087-2091. DOI: 10.1002/anie.201509131

*corresponding author |  co-first authorship

Patents:

2 Methods for Detecting Viral RNA Using ATP-Releasing Nucleotides
Eric T. Kool, Michael G. Mohsen
Publication number: WO 2022/115435. Jun 2, 2022
1 Amplified Isothermal Detection of Polynucleotides with ATP Release
Eric T. Kool, Debin Ji, Michael G. Mohsen
Publication number: 20170159112. Jun 8, 2017

Google Scholar: https://scholar.google.com/citations?user=_joWHJgAAAAJ&hl=en