Meeting program PDF download:10th-CryoEM-Schedule-Oct27-28
| Speaker | Lab | Institution | Title | ||
| Friday, Oct 27: Marsh Lecture Hall |
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| 08:15 AM – 09:00 AM | Registration, Breakfast | ||||
| 08:45 AM – 09:00 AM | Opening remarks | Jack Zhang & Joel Butterwick | |||
| Session 1a: | Hosted by Shenping Wu | ||||
| 09:00 AM – 09:20 AM | Talk 1 | Yong Xiong | Yong Xiong | Yale University | Visualizing human translation dynamics inside cells using in situ single-particle cryo-EM |
| 09:20 AM – 09:40 AM | Talk 2 | Jianbin Ruan | Jianbin Ruan | University of Connecticut Health Center | An unexpected regulation of Gasdermin pore formation revealed by cryo-EM |
| 09:40 AM – 10:00 AM | Talk 3 | Sayan Bhattacharjee | Joachim Frank | Columbia University | Mechanism of HflX-mediated recycling of E. coli ribosome studied by time-resolved cryo-EM |
| 10:00 AM – 10:20 AM | Talk 4 | Johannes Elferich | Nikolaus Grigorieff | UMass Chan Medical School | Workflows for In-Situ Structural Biology Using DeCo-LACE and cisTEM |
| 10:20 AM – 10:40 AM | Coffee Break | ||||
| Session 1b: | Hosted by Qinhui Rao | ||||
| 10:40 AM – 11:00 AM | Talk 5 | Tianming Fu | Tianming Fu | Ohio State University | Expect the unexpected: how protein oligomerization governs mechano-sensitivity |
| 11:00 AM – 11:20 AM | Talk 6 | Bonnie Su | Seychelle Vos | Massachusetts Institute of Technology | Distinct Negative Elongation Factor conformations regulate RNA polymerase II promoter proximal pausing |
| 11:20 AM – 11:40 AM | Talk 7 | Ling Xu | Anna Pyle | Yale University | Structural insights into intron branching and retrotransposition |
| 11:40 AM – 12:10 PM | Specially Invited Keynote Speaker | Xiangxi Wang | Xiangxi Wang | Institute of Biophysics, Chinese Academy of Sciences | Viral structure, antibody spectrum and vaccine design |
| 12:10 PM – 02:00 PM | Lunch & Poster session | ||||
| Session 2a: | Hosted by Boyuan Ma | ||||
| 02:00 PM – 02:20PM | Talk 9 | Marty Taylor | Marty Taylor | Harvard University | Structural analysis and inhibition of human LINE-1 ORF2 protein reveals novel adaptations and functions |
| 02:20 PM – 02:40PM | Talk 10 | Allen Guo | CEO of Shuimu | Shuimu BioSciences | Development of Cryo-EM Technologies at Shuimu BioSciences |
| 02:40 PM – 03:00 PM | Talk 11 | Roy Lederman | Roy Lederman | Yale University | Approaches for Exploring the Geometry of Molecular Conformations in Cryo-EM |
| 03:00 PM – 03:20 PM | Talk 12 | Le Xiao | Hao Wu | Harvard University / Boston Children’s Hospital | Cryo-EM structures of the active NLRP3 inflammasome disc |
| 03:20 PM – 03:40 PM | Coffee Break | ||||
| Session 2b: | Hosted by Ling Xu | ||||
| 03:40 PM – 04:00 PM | Talk 13 | Steve Bonilla | Steve Bonilla | Rockefeller | Using Cryo-EM to Solve the Structures of Conformationally Heterogeneous RNAs |
| 04:00 PM – 04:20 PM | Talk 14 | Emmanuel Smith | JEOL USA | JEOL USA | High-Throughput Single Particle Analysis using the JEOL CRYO ARM |
| 04:20 PM – 04:40 PM | Talk 15 | Chunyan Wang | Jun Liu | Yale University | A newly recognized small protein plays a critical role in bacteriophage T7 assembly |
| 04:40 PM – 05:00 PM | Talk 16 | Friederike Benning | Luke Chao | Harvard University |
Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly
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| 05:00 PM – 06:30 PM | Best Poster Awards announcement, Happy Hour, Social & Free discussion | ||||
| Saturday, Oct 28 Morning: Bass 305 |
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| 08:30 AM – 09:00 AM | Breakfast & free discussion | ||||
| Session 3a: | Hosted by Victor Gomes | ||||
| 9:00 AM – 9:20 AM | Talk 17 | Wenwei Li | Walther Mothes | Yale University | HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes |
| 09:20 AM – 09:40 AM | Talk 18 | Kexin Zhang | Nikolaus Grigorieff | UMass Chan Medical School | A Better Metric for Template Matching of Cellular Cryo-EM Images |
| 09:40 AM – 10:00 AM | Talk 19 | Bogdan Toader | Roy Lederman | Yale University | SGD for high-resolution cryo-EM reconstruction |
| 10:00 AM – 10:20 AM | Talk 20 | Michael Grunst | Walther Mothes | Yale University | Structure and Inhibition of SARS-CoV-2 Spike Refolding in Membranes |
| 10:20 AM – 10:40 AM | Coffee Break | ||||
| Session 3b: | Hosted by Shuhui Wang | ||||
| 10:40 AM – 11:00 AM | Talk 21 | Nikhil Malvankar | Nikhil Malvankar | Yale University | Cryo-EM “sequencing” reveals structures of microbial nanowires secreted by unique bipartite pili |
| 11:00 AM – 11:20 AM | Talk 22 | Ximena Zottig | Nikolaus Grigorieff | UMass Chan Medical School | Viral Translational Control Strategies Visualized with 2D Template Matching |
| 11:20 AM – 11:40 AM | Talk 23 | Seven Guo | Jun Liu | Yale University | Capturing and modeling the structural dynamics of the bacterial flagellar motor |
| 11:40 AM – 12:00 AM | Talk 24 | Jack Zhang | Jack Zhang | Yale University | In-situ cryo-EM/ET at sub-2 Å |
| Session EX: | Led by cryo-EM/ET experts at UMass and Yale | ||||
| 12:00 AM – 13:00 PM | Free discussion driven by open questions with all attendees involved; Snacks available |
Future Directions in Cryo-EM/ET Across Scales: From Atomic Structures to a Whole Cell | |||
| 13:00 PM | Closing remarks Jack Zhang & Joel Butterwick | ||||