Welcome to the website for collaborative projects between the Slav Bagriantsev and Elena Gracheva laboratories at Yale University. Our laboratories run a multidisciplinary research program to understand the molecular basis of temperature- and mechanoreception in the somatosensory system of vertebrates. We use electrophysiology, biophysics, biochemistry, deep sequencing and differential transcriptomics to clone and characterize sensory receptors and to understand their role in neurons.